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Original Article
Prevalence and Its Changes of Hepatitis B Viral Markers from 1988 to 1993 in Korean Children
Jae Geon Sim, Jeong Kee Seo, Seong Jae Suh
Clin Exp Pediatr. 1995;38(11):1535-1539.   Published online November 15, 1995
Purpose : Hepatitis B infection is prevalent in Korea and active immunization of Hepatitis B has been proceeded intensively during the last decade. This study was designed to evaluate the changes of the prevalence of hepatitis B surface antigen (HBsAg) and that of antibody (HBsAb) in Korean children from 1988 to 1993. We can estimate the prevalence and tendency of...
A Clinical Evaluation of the Gastrofiberscopy Studies in Children
Jung Ah Park, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hai Lee Chung, Young Dae Kwon, Jae Bok Park
Clin Exp Pediatr. 1995;38(11):1498-1505.   Published online November 15, 1995
Purpose : This study aimed to provide, as basic material, the experience of gastrofiberscopy in children and the clinical significance of Helicobacter pylori(H. pylori) infection in pediatric gastrointestinal disease. Methods : The objects were 99 patients(male 49, female 50) who underwent gastrofiberscopic examination in case of endoscopic indication at department of pediatrics of Taegu Hyosung Catholic University Hospital from March 1993...
Prospective, Controlled Trial with Dipheny1-dimethy1-dicarboxylate in Children with Chronic Liver Diseses : The Effect on Lowering Serum Aminotransferase Levels
Ji Eun Wunon, Sang Gil An, Ki Moon Cha, Yong Min Chung, Hee Sup Kim, Hann Tchah, Ho Jin Park
Clin Exp Pediatr. 1995;38(10):1378-1383.   Published online October 15, 1995
Purpose : The prospective cotrolled study was performed to identify the effect of the dipheny1-dimethy1-dicarboxylate(PMC) on lowering serum transaminases in children with chronic liver diseases. Methods : The twenty patients were paticipated in this study who were followed up in the Department of Pediatrics of the Seoul Red Cross Hospital because of the elevated levels of serum alaine aminotransferase(ALT) and aspartate...
Clinical and Histologic Changes in Children with Chronic Hepatitis B Virus Infection after Alpha Interferon Therapy
Kyung Mo Kim, Soo Jong Hong, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Joo Ryoung Huh
Clin Exp Pediatr. 1995;38(9):1232-1241.   Published online September 15, 1995
Purpose : Several trials in children for chronic hepatitis B have shown the efficacy of alpha interferon in eliminating hepatitis B virus replication, accompanied by an improvement in the liver cell damage. But reports about the alpha interferon therapy are rare in Korean children and there is no report about histologic changes even with adult. So we tried to...
Clinical and Histologic Findings and their Correlations in Children with Nodular Gastritis
Ki Moon Cha, Gi Euin Won, Hann Tchah, Ho Jin Park, Mi Kyoung Shin
Clin Exp Pediatr. 1995;38(8):1069-1076.   Published online August 15, 1995
Purpose : Recently, a wide application of gastrofiberscopy in the pediatric group have revealed that nodular gastritis is an unique disease in children and associated with Helicobacter pylori. The aim of this prospective study was to investigate the clinical and histologic features in children with nodular gastritis, and to assess corelation between both. Methods : During a period of 44 months(May 1991-December...
Upper Limit of Normal Value for Antistreptolysin O Titer of Healthy Children in Seoul
Sung Ho Cha, Yong Mook Choi, Sei Won Yang, Dong Hwan Lee, Chong Guk Lee, Chang Ho Hong
Clin Exp Pediatr. 1995;38(8):1061-1068.   Published online August 15, 1995
Purpose : We have found somewhat high titer of antistreptolysin O (ASO) accidentally when we had delineated normal carrier rate of beta hemolytic streptococci in rural area of Kangwon Province in 1991(1). We would like to know upper limit of normal value of ASO and re-valuated results which might be changed with different geographic areas, age, and prevalent rate...
Case Report
Angiodysplasia Involving the Sigmoid Colon in Children
Jae Young Kim, Kyung Won Hwang, Young Ho Ahn, Jin Bok Hwang, Chang Ho Han, Hae Lee Chung, Young Dae Kwon, Yong Jin Kim
Clin Exp Pediatr. 1995;38(7):993-999.   Published online July 15, 1995
Angiodysplasia(AD) of the gastrointestinal(GI) tract in children is a very rare cause of bleeding and thought to be a distinct clinicopathologic entity distingishing from the classic adult-type AD by its different clinical settings and diverse histology. We report two cases of AD involving the sigmoid colon in children. The cases, 6-year-old girl and 11-year-old boy, were preoperatively suspected by colonoscopy and...
Original Article
A Clinical Study of Tsutsugamushi Disease in Children
Jee Yeon Song, Ji Whan Han, Sung Soo Hwang, Kyung Yil Lee, Kyong Soo Lee
Clin Exp Pediatr. 1995;38(5):641-648.   Published online May 15, 1995
Purpose : Recently in Korea, there has been an increasing concern regarding Tsutsugamus-hi disease. This disease is increasingly reported in children. The purpose of this study was to c-onsider the possibility that Tsutsugamushi disease may be diagnosed as eruptive disease or F UO( fever of unknown origin) Methods : We reviewed 17 clinically or serologically confirmed cases of Tsutsugamushi dis-ease from...
A Study of Bone Marrow Density in Korean Children of Normal Growth and Development
Byung Yoen Kim, Young Guk Kim, Young Jun Kim, Kee Hwan Yoo, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1995;38(5):612-618.   Published online May 15, 1995
Bone mineral densitometry is a useful procedure for the early detection of metabolic bone diseases and bone density changes caused by long term drug use. Dual energy X-ray absorpt- iometry(DEXA), a recently developed diagnostic radiologic method for evaluating bone mineral density is widely used because of its high sensitivity, easily obtaine results. and low dose radi- ation exposure. The study...
Incidence and Complications of Obesity in Pubescent School Children
Boo Hyun Han, Duk Hi Kim, Yoo Kyung Park, Jong Ho Lee, Ho Seong Kim
Clin Exp Pediatr. 1995;38(4):520-528.   Published online April 15, 1995
Purpose : In recent years, obesity in children has become one of the major nutritional problems, and the trend is that number of obese children is increasing. The purpose of this research is to examine the incidence of obesity in pubescent school children in Seoul and Cheju, and to analyze body fat component, complications and eating habits of those obese...
Serum Lipids in Children and Adolescents with Family History of Coronary Artery Diseases
Kee Hyoung Lee, Chang Sung Son, Joo Won Lee, young
Clin Exp Pediatr. 1995;38(4):482-492.   Published online April 15, 1995
Purpose : Atherosclerotic change begins in childhood, elevated blood lipid levels and a family history of premature coronary vascular diseases are important risk factors for coronary artery disease. Identification, follow-up and treatment of children at high risk of cardiovascular diseases are very effective and important for prevention of future coronary artery diseases. The purpose of this study is to determine...
Infections in Children with Neoplastic Disease
Eun Hwa Choi, Jin Won Pyo, Jin Young Park, Kyung Bae Kwon, Bo Young Yun, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn
Clin Exp Pediatr. 1995;38(3):366-377.   Published online March 15, 1995
Purpose : Infection is a major complication in patients with malignant disease. This study was performed to identify the causes and the etiologic agents of febrile infections and to characterize the clinical courses including the response to antimicrobial agents inpediatric cancer patients. Methods : This study reviewed 274 febrile episodes occurring in 163 children with neoplastic disease which were indentified prospectively...
Clinical Characteristics of Childhood Cerebrovascular Disease and Analysis on the Prognostic Factors
Yong Seung Hwang, Moon Sun Yang
Clin Exp Pediatr. 1995;38(3):353-365.   Published online March 15, 1995
Purpose : Cerebrovascular disease in children is more common than was once recognized and the etiology and prognosis of the disease in children are quite different from those of adults. Recently according to medical reports and clinical experiences, the incidence of childhood cerebrovascular disease is increasing in Korea. To clarify the clinical features of childhood cerebrovascular disease and to analyze its...
Peptic Ulcer Disease in Infants and Children
In Sheol Park, Nam Su Kim, Poong Man Jung
Clin Exp Pediatr. 1995;38(3):339-346.   Published online March 15, 1995
Purpose : This study was performed to be helpful in early diagnosis and treatment of the children with peptic ulcer disease. Methods : The authors observed 36 children with peptic ulcer disease who had been admitted to Hanyang University Hospital during the 11 year 4 mont period from January 1981 to April 1992 retrospectively. The diagnosis was established in 33.3% by...
A Study on Clinical Characteristics of Maxillary Sinusitis in Korean Children
Dong Nam Kim, Sung Hee Oh, Hahng Lee
Clin Exp Pediatr. 1995;38(3):319-327.   Published online March 15, 1995
Purpose : Paranasal sinusitis, easily overlooked owing to it's benign symptomatology, should be considered when the upper respiratory tract infction persists longer than seven days. Without early recognition and appropriate management, the disease will take a chronic course and the incidence of complications will be increased. The significance of paranasal sinusitis among Korean children has not appropriately been appreciated; therefore,...
Observation of Social Background and Disease Patterns of Children in an Institute for Adoption (the 3rd report)
Jae Bong Kwon, Cheol Soon Park, Jae Wook Ko, Myung Ik Lee, Don Hee Ahn
Clin Exp Pediatr. 1995;38(1):81-90.   Published online January 15, 1995
Purpose : A Study was undertaken to assess the family background of abandonment and clinical and social aspects in an institute for foreign adoption. The results were compared to the previous two reports from the institute. Method : A sample of 1,728 children from 1987 to 1992 formed the subjects of the study by the medical records in the institution. Results :...
Serum Total Cholesterol and HDL Levels in Healthy Korean School Children: Do They Correlate with Obesity?
Jae Geon Sim, Mi Za Chun, Moses Whang
Clin Exp Pediatr. 1994;37(11):1579-1585.   Published online November 15, 1994
Purpose : The cut-off value for hypercholesterolemia and normal HDL levels for Korean children are still not established despite increasing hypercholesterolemia with recent socioeconomic change. One of the aims of this study its to screen the serum total cholesterol and HDL levels in normal Korean school children, and another is to evaluate the relationships between serum lipid levels and obesity. Methods...
Right Ventricular Area, Dimension, and Volume Measured by Two-dimensional Echocardiography in Normal Children
I-Seok Kang, Jung-Yun Choi
Clin Exp Pediatr. 1994;37(10):1340-1349.   Published online October 15, 1994
The usefulness of two-dimensional echocardiography to measure the right ventricular volume was assessed in 58 normal children(mean age 5 years and 3 months). From the apical 4-chamber view(A4CV), the subcostal RV sagittal view(SCRVSV), the subcostal right anterior oblique view(SCRAOV), and the subcostal RV coronal view(SCRVCV), the dimensions and areas of the right ventricle were measured. The right ventricular volumes and...
Study on Child Mortality among Korean Children
Beom Soo Park, Moo Song Lee, Seung Pil Jeong, Yoon Ok Ahn
Clin Exp Pediatr. 1994;37(9):1264-1272.   Published online September 15, 1994
To estimate the child and infant mortality rates among Korean children, a mortality survey was carried out in the province of Kyongsangnam¡¤buk-do. The study popolation are the beneficiaries of Korea Medical Insurance Coorporation(KMIC), Kyongsangnam¡¤buk-do area, among which the 3,867 and 1767 deaths occurred from Januray, 1989 to December, 1990 in Kyongsangnam-do area and from January, 1991 to December, 1991 in...
A Study on Blood Lead Levels in Pediatric Inpatients
Young Ho Lee, Hyoung Shim Chang, Bong Keun Choi, Kyu Geun Hwang, Ahn Hong Choi
Clin Exp Pediatr. 1994;37(8):1111-1115.   Published online August 15, 1994
Lead is one of the most widespredad environmental toxins and its poisoning in children was considered a rarity, usually resulting from unique circumstances such as inappropriate use of lead-based body cosmetics or direct administration of lead-containing folk medicines. The increasing concern about children with lower levels of lead exposure has developed, but there are no data regarding the mean blood...
Pheochromocytoma in Children
Tae Sue Ha, Jae Hong Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hyung Ro Moon, Gui Won Park
Clin Exp Pediatr. 1994;37(7):961-968.   Published online July 15, 1994
We Reviewed 10 hypertensive children with pheochromocytoma retrospectively and the following results were obtained. 1) Out of 10 patients, 7 were male and 3 female. Age ranged from 5.5 years to 13.8 years and their median age was 9.9 years. 2) They complained of sweating, lethargy, headache, or chest pain and so on, Hypertension were noticed in all patients. Heart murmurs were...
A Clinical Observation on Lupus Nephritis in Children
Kang Mo Ahn, Jae Sung Ko, Hye Won Park, Il Soo Ha, Hae Il Cheong, Yong Choi, Hee Joo Kim
Clin Exp Pediatr. 1994;37(6):842-849.   Published online June 15, 1994
We reviewed the clinical features, histrologic patterns and clinical courses of 30 children with lupus nephritis retrospectively, and the results were summerized as follows; 1) The male to female ratio was 1:2.8, and the mean age at the onset was 108/12 years. 2) The clinical symptoms were diverse, and malaise, weight loss, anorexia, fever and malar rash were the most frequent findings. 3)...
Prevalence of Epstein-Barr Virus (EBV) Antibody in Korean Children
Sei Ho Oh, Young Ah Lee, Woong Young Moon, Tae Sun Won, Young Seo Park, Hyung Nam Moon, Chang Yee Hong, Dae Won Kim
Clin Exp Pediatr. 1994;37(6):804-811.   Published online June 15, 1994
Recently, cases with typical clinical manifestations of infectious mononucleosis are increasing in Korea. So, to evaluate the recent epidemiology of EBV infection in Korea, we performed EBV serologic antibody tests for IgG antibody to EBV-viral capsid antigen (VCA) and antibody to EBV-associated nuclear antigen (EBNA) among the 108 healthy Korean infants and children whose ages were from newborn to 15...
A Clinical Study on Chronic Hepatitis b in the Children
Bon Su Koo, Han Sang Joo, Yung Tak Lim, Hee Ju Park
Clin Exp Pediatr. 1994;37(6):767-775.   Published online June 15, 1994
The author observed clinical study and response of -interferon treatment of 43 cases of chronic hepatitis who were admitted to Department of Pediatrics Pusan National University College of Medicine during the period of 4 year 6 months from Jenuary, 1988 to Jun, 1992. The results were as follows: 1) Of 43 patients with chronic hepatitis CPH was 17 cases (39.5%) and CAH...
Coxiella Burnetii Infection In Patients With Various Diseases
Kyo Sun Kim, Won Young Lee
Clin Exp Pediatr. 1994;37(3):356-367.   Published online March 15, 1994
Coxiella burnetii(C. burneii) was first recognzed as the agent of Q fever in 1937. Q fever is an acute self-limited febrile illness. However, it manifests with several clinical symptoms depending upon the organs that are involved. The association of C. burnetii with human neoplasia has been rarely reported. We prospectively studied the 55 patients with fever of unknown origin, pneumonia, hepatos-plenomegaly,...
The Effect of Alfacalcidol in the Treatment of Idiopathic Myelofibrosis in Children
Soon Ki Kim, Jeong Hee Kim, Dae Hyun Lim, Jong Woon Choi, Byong Kwan Son, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(3):339-346.   Published online March 15, 1994
Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extramedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposition in IMF using 1, 25-dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F = 1:4) with IMF before and after treatment...
Choleithiasis in Childhood
Soon Young Kim, Jeong Kee Seo
Clin Exp Pediatr. 1994;37(1):70-77.   Published online January 15, 1994
Nineteen children found to have gallstones at Seoul National University of Children's Hospital form Jun. 1982 to Jun. 1992 wee reviewed. The results were as follows: 1) The mean age was 10 years, with 9 boys and 10 girls. Most of the cases (63%) were over 10 years of age. 2) Clinical manifestations were abdominal pain (14 cases), naused and/or vomiting (5 cases), fever...
The Effect of Prolonged Treatment in Children with Chronic Hepatitis B with Combination of Alpha-Interferon and Acyclovir
Jeong Ok Hah, Kyoung A Lee
Clin Exp Pediatr. 1993;36(12):1701-1706.   Published online December 15, 1993
This study was conducted to evaluate the effect of prolonged treatment in children with chronic hepatitis B will combination of alpha-interferon and acyclovir. The study population consisited of & patients with chronic hepatitis B who showed histological findings compatible with chronic active hepatitis (4 cases) or chronic persistent hepatitis (3 cases) on liver biopsy and had elevated AST and ALT with...
Esophageal Varix in Children - Endoscopic Evaluation and Clinical characteristics-
Soon Young Kim, Jeong Kee Seo
Clin Exp Pediatr. 1993;36(12):1691-1700.   Published online December 15, 1993
Fifty five children with encoscopically proven esophageal varices form Jul. 1987 to Dec. 1992 were analyzed for endoscopic and clinical characteristics. The results were as follows : 1) According to etiological classification of portal hypertension in 55 cases, 35 cases showed intrahepatic causes (64%) and cases had extrahepatic causes (36%). The most common clinical manifestation on admission was hematemesis (42%) and abdominal mass...
A Clinical Study of Bronchial Asthma in Children
Seung Hee Park, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1993;36(9):1291-1299.   Published online September 15, 1993
This report is a clinical analysis and comparative study with previous report of bronchial asthma at National Medical Center on bronchial asthma in children who were admitted to the MP dept. of national Medical Center from January 1987 to December 1990. The results of the study were as follows: 1) The out-break ratio of bronchial asthma is 3.7% of hopitalized children which...
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